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A mitochondria-targeted covalent organic framework (COF) prodrug that is selectively activated by high intramitochondrial GSH levels was shown to trigger catalase collapse within the organelle, thereby amplifying local chemodynamic therapy (CDT) through enhanced ROS accumulation and mitochondrial dysfunction

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In the first phase, two equivalents of ATP are used to convert glucose to fructose 1,6-bisphosphate (F1,6BP)

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Variation: Size: CoQ10 200 + PQQ 20 is a uniquely comprehensive formula designed to promote optimum cellular energy by providing high levels of both CoQ10 and Pyrroloquinoline Quinone (PQQ)