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[DOI] [PMC free article] [PubMed] [Google Scholar] Broad RC, Bonneau JP, Hellens RP, Johnson AAT
Extracellular cysteine can also directly be taken up by cultured astrocytes and used for GSH synthesis, but its disulfide cystine, that is transported into rat astrocytes mainly by the cystineglutamate antiporter X C , serves as the preferred extracellular substrate for the cytosolic cysteine needed for astrocytic GSH synthesis (Kranich et al
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Thus, both DHA reduction and hyperoxy radicals generated via iron redox reactions contribute to a hemolytic phenotype in G6PD def patients

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doi: 10.7812/TPP/18-068 112
