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Available from: Accessed on 24/09/2025 Agenzia Italiana del Farmaco

Furthermore, supplementation with LC has a positive impact on numerous essential pathways involved in pathological skeletal muscle loss, which might explain at least some of the anti-catabolic benefits and improvements in fatigue-related metrics seen in chronic illness people who received it (Montesano et al., 2015, Ringseis et al., 2013)

pp 14171426 Rapoport SI

For example, studies show improvements in running speed, increased maximal oxygen uptake, and decreases in average oxygen consumption, heart rate, and lactic acid

(PubMed) Wijdicks EF

After their eligibility was confirmed, the participants in both cohorts were then randomized 1:1 to receive LCLT supplement (Group A) or placebo (Group B) for 21 days in balanced blocks (Figure 1)