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While there is no established link between these medications and structural changes to taste buds themselves, the functional experience of taste can be significantly modified during treatment, impacting dietary preferences and eating behaviors in ways that may contribute to the therapeutic effects of these agents

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NMNAT3, mitochondria) and were reported to regulate NAD + levels in their respective cellular compartment, but also to influence other intracellular NAD + stores 4,249,250

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"Circadian regulation of NNMT expression and its role in metabolic homeostasis." Journal of Biological Rhythms, 36(4), 342-356