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The KTTKS sequence is derived from the procollagen

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thus the engineered hydrogel is named as self-diagnostic that can be used to alter wound microenvironment to promote wound healing in an intelligent manner [179]

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De Simone R, Ajmone-Cat MA, Carnevale D, Minghetti L (2005) Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures
