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[1] Unlike amphetamine abuse, where drug tolerance necessitates escalating doses to achieve the same effect, tolerance to clinically relevant doses of amphetamine plateaus after the initial titration period, and "drug holidays" (i.e., temporary treatment discontinuation) are not required to prevent the development of tolerance

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miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-B/NLRP3 pathway

The results demonstrate that sperm viability and sperm count decrease and the sperm deformity rate increases as the altitude increases, and the effects are most obvious at an altitude of 6000 m