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Clin Med (Lond)

Through this updated review, we aim to contribute to the evolving understanding and management of fibromyalgia, offering insights into the diverse tools available to improve the lives of those affected by this challenging condition

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China J Chin Mater Med 45(24):58665876 Decombaz J, Deriaz O, Acheson K, Gmuender B, Jequier E (1993) Effect of l-carnitine on submaximal exercise metabolism after depletion of muscle glycogen

ALA may be helpful for: People with diabetic neuropathy: ALA has the strongest clinical evidence for reducing nerve pain and improving quality of life in this group.1 Those with type 2 diabetes or metabolic syndrome: Modest improvements in insulin sensitivity and blood sugar markers have been observed in some studies.24 People with high oxidative stress: Research shows that ALA can help lower oxidative stress markers like CRP in individuals with chronic inflammation or metabolic risk factors.27 Those with nerve-related conditions or mitochondrial dysfunction: Early research suggests ALA may help support nerve health in contexts like multiple sclerosis.3 However, ALA may not be appropriate if: Youre generally healthy and eat a balanced diet Your body naturally produces some ALA, and small amounts are found in foods like spinach, broccoli, red meat, and organ meats.41 In healthy individuals, taking an ALA supplement may offer little to no added benefit

During the familiarization session and following informed consent, a research nutritionist and a professional strength and conditioning specialist met with each participant and explained in detail the strength training regimen as well as the nutritional and supplement requirements for the study period

Older patients Evidence of low-to-moderate quality showed that CBT-I enhanced older people' sleep efficiency, wakefulness following sleep onset, and sleep onset latency