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Studies in GPR55 knockout mice have shown reduced inflammatory and neuropathic pain in models of inflammation induced by adjuvants and partial nerve ligation [29]

LGSH derived from MGO is subsequently hydrolyzed by glyoxalase 2 (GLO2) to produce D-lactate and glutathione [33]

Serum from these women was analyzed for complexed prostate specific antigen (cPSA) and free prostate specific antigen (fPSA), by fifth generation assays with limits of detection of around6 and 140 fg/mL, respectively

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Crit Rev Toxicol 51:634652