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It is plausible that EBV lytic genes, along with the various cellular responses induced during EBV infection, may affect the cellular redox state and antioxidant mechanisms, including the modulation of GPX4 expression

doi:10.1053/j.gastro.2010.09.039

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This evidence supports a multi target therapeutic paradigm that is consistent with the multifactorial nature of ASD and suggests that combined interventions, for example, omega3 with vitamin D or vitamin E, or cysteine rich proteins to boost glutathione, may exert additive or synergistic effects across redox, mitochondrial, and immune pathways (Politi et al., 2008

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