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In studies of healthy individuals, Bryrup et al
Toxicity threshold of quinine hydrochloride following low-level repeated dosing in healthy volunteers
150 mM.L 1 NaCl
Treatment of human and mouse small intestine organoid models with SCFAs increases the number of GLP-1-producing cells twofold 284 , and SCFA infusion activates colonic EECs to increase GLP-1 release in mice 281
